Vitamin c
IV Infusion
Vitamin C (Ascorbic acid)- intravenous infusion
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INDICATIONS:
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IMMUNE BOOSTER
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SKIN BRIGHTENING
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ANTI-AGEING
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ANTIOXIDANT
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ANTIVIRAL
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DETOXIFICATION
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REDUCES FATIGUE
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ANTI-CANCEROUS
Benefits:
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• Vitamin C is required for the biosynthesis of collagen, L-carnitine, certain neurotransmitters and protein metabolism.
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• It helps maintain healthy skin, blood vessels, bone and cartilage.
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• Vitamin C is also an important physiological antioxidant below 20 grams and it is a pro-oxidant above 20 grams (used for anti-cancer therapy)
• Regenerates other antioxidants within the body, including alpha-tocopherol (vitamin E)
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• Antiviral effect can be achieved with intravenous concentrations (not possible with oral concentrations. Oral Vitamin C reaches a peak plasma limit due to GI absorption saturation and increased renal clearance)
• At a high concentration Vitamin C destroyed 72% of the histamine present in the medium! It can help with allergies!
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• Collagen neogenesis via fibroblast activation
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• It helps with better wound healing and postoperative recovery
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Cardiovascular effects
• Reduce monocyte adherence to endothelium and improve endothelium-dependent nitric oxide production and vasodilatation.
• Reduce vascular smooth-muscle-cell apoptosis which prevents plaque instability in atherosclerosis.
Vitamin C deficiency can cause:
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• Fatigue, malaise and inflammation of gums
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• Impaired collagen synthesis results in connective tissue weakness causing petechiae, ecchymosis, purpura, arthralgia, poor wound healing, hyperkeratosis and corkscrew hairs.
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• Depression
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• Iron deficiency anaemia due to increased bleeding and decreased non-heme iron absorption
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Groups at risk of Vit C inadequacy
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- smokers (76% of smokers will have an inadequate intake of Vit C)
- passive smokers
- malabsorption
- cancer
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Intravenous Nutrition Therapy is preferred over oral tablets or intramuscular injections because:
-it bypasses gastrointestinal (GI) absorption and biotransformation in the liver ensuring bio-availability of the micronutrients in high concentrations (not bound to plasma proteins) and gives desired results quickly
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- total concentration of intravenous infusion/injection is available to the tissues
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- higher IV nutrient concentrations can be given than is possible by mouth without the intestinal side effects, i.e. diarrhoea following high oral doses of magnesium or vitamin C.
*Suitable for males and females between 18-60 years
* Patients undergoing chemotherapy/radiation must consult with their oncologist before taking vit C
(written letter required)
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!!! VERY IMPORTANT!!!
Blood tests are required before commencing Intravenous Nutrition Therapy.
The following blood test results are required:
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FULL BLOOD COUNT
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LIVER FUNCTION
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KIDNEY FUNCTION
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G6PD (Glucose-6-Phosphate Dehydrogenase)
These blood tests can be done privately at my clinic ( Price £200)
or you can do them elsewhere.
​
*Blood is collected on Saturday morning only. If you wish to make booking for this please send me a message via social media or email aestheticnursesclinic@gmail.com
Contraindications:
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allergy to vitamin C or any of the other ingredients
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if you suffer from oxalate urolithiasis (a type of kidney or bladder stone) or hyperoxaluria (a condition, where you have too much oxalate in your urine)
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if you suffer from an iron storage disorder/iron overload (e. g. thalassemia, hemochromatosis, sideroblastic anaemia, erythrocyte concentrate transfusions)
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if you have a severe renal insufficiency (impaired kidney function or kidney failure)
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if you have a glucose-6-phosphate dehydrogenase deficiency/defect (inherited disorder of red blood cell metabolism)
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Medications: Deferiprone, Desferrioxamine (taken with Vit C can cause disturbance of the heart function)
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Pregnancy and breast-feeding
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Very high or very low blood pressure
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Poorly controlled diabetes
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Patients on antipsychotic drugs: phenylalanine
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Chronic liver disease & hepatic encephalopathy
The following medicinal drugs reduce the concentration of vitamin C in your body and thus might reduce the effectiveness of Ascorbic Acid:
- Acetylsalicylic acid (anti-inflammatory drug) such as aspirin (Large doses of vitamin C may lower the effectiveness of oral anticoagulants)
- Nicotine from cigarettes
- Alcohol
- Appetite suppressants (e.g. fenfluramine)
- Iron (taken as a food supplement)
- Medicines used to treat epilepsy (e.g. phenytoin)
- Oral contraceptives which contain oestrogen (e.g. “the pill”)
- antibiotics (e.g. tetracycline)
- Fluphenazine (for mental disorders): Blood concentrations might decrease due to Vitamin C
Therapy
-Aluminium antacids in combination with vitamin C may lead to higher blood aluminium levels
- Is vitamin C infused before or after the chemo-/radiotherapy, a temporal distance
of 24 hours is recommended
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Health risks from excessive Vit C
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- Kidney stones in individuals with renal disease and pre-existing hyperoxaluria
- For people with hereditary hemochromatosis (which is a contraindication to this treatment) high dose of Vit C can result in even more iron overdose and result in tissue damage
- Too much of high doses given too often can cause iron overload
- May induce muscle cramps->Vit C requires calcium supplementation!
- Insulin-dependent diabetics have to be careful of high doses of Vit C (more details on a consultation)
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GLUTathione
IV Infusion
GLUTATHIONE- The ‘Master’ Antioxidant
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What is glutathione?
• A tripeptide composed of the 3 amino acids glutamic acid (excitatory), cysteine (excitatory), and glycine (inhibitory).
• Is found in all cells in the body, in the bile, in the epithelial lining fluid of the lungs and at much smaller concentrations in the blood.
• All 3 amino acids in the tripeptide are glucogenic (sugar-burning).
Functions of Glutathione:
• Performs Phase I & II detoxification in the liver of heavy metals, organophosphate pesticides, chlorinated hydrocarbon solvents, estradiol, prostaglandins, leukotrienes, acetaminophen, and other
foreign chemicals.
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• Primary detoxifier of heavy metals
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• First line of protection against environmental chemicals and toxins.
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• Master antioxidant in each cell. Defence against oxidative stress
• Regulates the cell cycle, DNA and protein synthesis, proteolysis, and gene expression.
• Participates in bile production.
• Transports amino acids especially cysteine into kidney cells.
• Protects thyroid cells from self-generated hydrogen peroxide.
• Chelator of lead, mercury, cadmium and arsenic (present in cigarette smoke - beware passive smokers).
• Can prevent or reverse alcohol-induced fatty liver, cirrhosis, hepatitis, and liver tumours.
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• Cardiovascular system enhancer
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• It transforms haemoglobin into its reduced state, enabling it to accept oxygen and carry it to the cell
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• Major protector of the immune cells and the immune system
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• Only antioxidant that can recycle itself
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• Skin lightening (anti-melanogenic effect)
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INDICATIONS/BENEFITS:
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- Increased energy
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- Slows down the ageing process
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- Reduces muscle& joint discomfort
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- Strengthens immune system
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- Detoxifies the liver and cells
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- Improves mental focus and clarity
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- Improves quality of sleep
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- Reduces the effects of stress
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- Improves the skin
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- Athletic performance and recovery
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- Skin lightening (melasma, hyperpigmentation)
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Depletion can cause:
• Chronic fatigue syndrome.
• GSH deficiency is of great significance in the pathogenesis of Diabetes Mellitus.
• Glutathione depletion may contribute to the production of phototoxicity by UVB, UVA and by PUVA
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Contraindications:
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- asthma (caution)
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- epilepsy (glutamate is an excitatory amino acid)
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- bipolar disorders (glycine)
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- may decrease the effectiveness of Clozapine
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- pregnancy and breastfeeding
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- very high or very low blood pressure
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- poorly controlled diabetes
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- patients on antipsychotic drugs: phenylalanine
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- chronic liver disease & hepatic encephalopathy
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!!! VERY IMPORTANT!!!
Blood tests are required before commencing Intravenous Nutrition Therapy.
The following blood test results are required:
-
FULL BLOOD COUNT
-
LIVER FUNCTION
-
KIDNEY FUNCTION
-
G6PD (Glucose-6-Phosphate Dehydrogenase)
These blood tests can be done privately at my clinic ( Price £200)
or you can do them elsewhere.
​
*Blood is collected on Saturday morning only. If you wish to make booking for this please send me a message via social media or email aestheticnursesclinic@gmail.com